Preliminary study on antimicrobial activities of skin mucus fromby-catch of Elasmobranch species

Skates and rays, which are widely encountered in the by-catch of fisheries activities from Sea Marmara banned for sale by regulation, species that discarded if caught. For this reason, our study, we aimed to determine bioactive potentials these species, considered fishing waste, investigating skin secretions microbial flora. In both flora mucus contents Dasyatis pastinaca (Linnaeus,1758), Myliobatis aquila (Linnaeus, 1758), Raja clavata 1758) caught were investigated their potential antimicrobial activities. A total 164 bacteria isolated epidermal three batoid species. Antibacterial activity was observed against Escherichia coli, Vancomycin-resistant Enterococcus faecium, E. faecalis, Bacillus subtilis. Additionally, highest antibacterial R. clavata. Mouse fibroblast cell viability challenged with secretions. M. exhibited no observable change after 24 48 hours. The assays indicated isolates have opportunistic pathogens.